Psoriasis, a chronic autoimmune condition affecting the skin, is closely linked to inflammation in the body. Dr. Chanu Dasari’s Mind-Gut-Immunity Method offers a holistic approach to addressing psoriasis by targeting the root causes of inflammation. By understanding the biochemical pathways of inflammation and incorporating dietary and lifestyle changes, individuals can reduce symptoms and promote long-term healing.

Understanding Inflammation and Psoriasis

Inflammation is the body’s natural response to injury or infection, but in autoimmune diseases like psoriasis, this response becomes dysfunctional. Psoriasis symptoms—such as red, scaly patches of skin—are often exacerbated by chronic inflammation. Dr. Dasari identifies three key pathways of inflammation that significantly impact psoriasis:

1. Histamine Pathway

Histamine, a compound produced in the gut by bacteria, plays a major role in triggering allergic and inflammatory reactions.

• Gut Connection: Approximately 70–80% of the immune system resides in the gut, making gut health essential for managing psoriasis.
• Dietary Triggers: Foods high in histidine (a precursor to histamine) and histamine-stimulating foods—such as shellfish, peanuts, pineapples, and processed carbohydrates—can worsen symptoms.
• Solution: Reduce histamine production by:
  • Avoiding sugary and starchy foods.
  • Eating more leafy greens and fiber-rich foods.
  • Supporting gut health with probiotics and ensuring regular bowel movements (2–4 times a day).

2. Arachidonic Acid Pathway

Arachidonic acid, a type of fat found in animal-derived products, contributes to inflammation in the body.

• Sources: Red meat, poultry, and full-fat dairy are high in arachidonic acid.
• Impact: These foods can increase cytokine production, intensifying the inflammatory response.
• Solution:
  • Reduce or eliminate animal fats from the diet.
  • Opt for plant-based protein sources and phytonutrient-rich foods.

3. TNF-α and IL-6 Pathway

Tumor Necrosis Factor-Alpha (TNF-α) and Interleukin-6 (IL-6) are cytokines that signal inflammation in the body. Elevated levels of these markers are common in psoriasis patients.

• Triggers: Diets high in animal fats and low in phytonutrients can increase TNF-α and IL-6.
• Vitamin D Deficiency: Low vitamin D levels are associated with higher inflammation.
• Solution:
  • Increase phytonutrient intake through vegetables, berries, and spices like turmeric.
  • Supplement with vitamin D to support a balanced immune response.

Holistic Strategies for Managing Psoriasis

To address psoriasis holistically, it’s essential to adopt a comprehensive approach that prioritizes diet, gut health, and inflammation control.

1. Focus on Gut Health

Since most inflammation begins in the gut, improving digestive health is a cornerstone of psoriasis management.

• Eat prebiotic and probiotic-rich foods to nourish healthy gut bacteria.
• Limit processed foods and sugars that feed harmful microbes.
• Support detoxification with cruciferous vegetables like broccoli and kale.

2. Adopt an Anti-Inflammatory Diet

A diet rich in phytonutrients helps downregulate inflammation and supports skin health.

• Incorporate Phytonutrients:
  • Polyphenols: Found in green tea, turmeric, and berries, these compounds reduce oxidative stress.
  • Chlorophyll: Present in leafy greens, it helps detoxify the liver and reduce inflammation.
  • Isothiocyanates: Sulforaphane from broccoli sprouts is a powerful anti-inflammatory agent.
• Replace saturated animal fats with healthy fats from olive oil, avocados, and nuts.

3. Limit Sodium Intake

Excessive salt consumption can worsen inflammation by activating specific immune cells.

• Avoid processed and packaged foods high in sodium.
• Monitor sodium levels in hidden sources like chicken and condiments.

4. Supplement Wisely

Adding the right supplements to your routine can bridge nutritional gaps.

• Vitamin D: Helps lower TNF-α and IL-6 levels, supporting immune balance.
• Probiotics: Aid in maintaining a healthy gut microbiome.
• Omega-3 Fatty Acids: Found in flaxseeds and walnuts, these reduce inflammation.

Lifestyle Changes to Support Holistic Healing

In addition to dietary adjustments, lifestyle changes play a crucial role in managing psoriasis.

1. Prioritize Sleep

Quality sleep helps regulate inflammation and supports immune function. Aim for 7–9 hours of uninterrupted sleep each night.

2. Manage Stress

Chronic stress can exacerbate inflammation and psoriasis symptoms. Incorporate stress-reduction techniques like yoga, meditation, or deep breathing exercises into your daily routine.

3. Stay Active

Regular exercise boosts circulation, improves skin health, and reduces stress. Choose low-impact activities like walking or swimming to avoid aggravating joint pain in psoriatic arthritis.

Taking Control of Your Psoriasis

Psoriasis is a complex condition, but addressing its root causes through holistic treatments can lead to lasting relief. By focusing on gut health, adopting an anti-inflammatory diet, and making strategic lifestyle changes, you can significantly reduce symptoms and improve overall well-being.

For personalized guidance and support, schedule a discovery call with Dr. Chanu Dasari at MGI Clinics. Our Case Studies page features stories of patients who have successfully managed their conditions through the Mind-Gut-Immunity Method. Your journey to clear skin and better health starts today.

Start Your Journey to Better Health Today

Discover the transformative power of the Mind-Gut-Immunity Method! Over the past decade, Dr. Dasari has helped countless clients reduce inflammation and find relief from autoimmune issues, often in just 3-6 weeks. Now, you can start your journey to better health with our free training. Click the link below, choose your condition, and learn how our proven approach can help you feel better fast. 

About the Author

Dr. Chanu Dasari, a distinguished clinician with a career spanning renowned institutions like Vanderbilt University, Oxford University, and the University of California, has made significant contributions to medical research and practice. His work, published in top peer-reviewed scientific journals and adopted by the US Department of Health, highlights his commitment to advancing healthcare. Dr. Dasari is board-certified by the American Board of Medical Specialties and the American College of Surgeons, with a specialization in hernia repair, gallbladder removal, cysts, digestive disease, and cancer. As the founder of the Mind-Gut-Immunity Clinic, he draws from personal experience with autoimmune and digestive dysfunction to lead a team dedicated to patient-centered care using evidence-based protocols.